OA KNEE - Dissertations.se

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At a time point after an intravenous or intra-articular negatively charged gadolinium agent is injected Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) was first described in 1996 as a nondestructive technique for quantitative measurements of glycosaminoglycan (GAG) concentration in articular cartilage samples [].Its translation to clinical platforms as a means of interrogating the molecular aspects of cartilage was demonstrated in 1997 with illustrative examples of apparent … 2013-07-01 dGEMRIC scan was obtained. Patients with general contraindica-tions for MRI scanning, a known allergic reaction to gadolinium-containing contrast agents or with a history of kidney pathology wereconsiderednoteligibleforinclusion.If,duringarthroscopy,the treating physician found that the lesion or other cartilage surfaces dGEMRIC effectively detected differences in cartilage quality within knee compartments before and after HTO, but no changes due to HTO were detected. Hardware removal post-HTO seems essential for adequate T(1)Gd interpretation. T(1)Gd was correlated to improved clinical scores on a subscore level on … 2013-04-01 Ground Floor Suite 3-6, 100 Victoria Parade East Melbourne VIC 3002 Ph: 03 9667 1667 Fax: 03 9667 1666 BACKGROUND: Three-dimensional (3-D) delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) helps quantify biochemical changes in articular cartilage that correlate with early-stage osteoarthritis. However, dGEMRIC analysis is performed slice by slice, limiting the potential of 3-D data to give an overall impression of cartilage biochemistry.

At similar time points clinical improvement was monitored using the KOOS and Lysholm questionnaires. Per MRI scan several regions-of-interest (ROI) were defined for different locations in the joint. Design: Thirty-one patientswitha focalcartilage lesion underwent a dGEMRIC scanpriortocartilage repair surgery and at 3 and 12 months follow-up. At similar time points clinical improvement was monitored using the Knee injury and Osteoarthritis Outcome Score (KOOS) and Lysholm questionnaires. Per MRI scan Design: Thirty-one patients with a focal cartilage lesion underwent a dGEMRIC scan prior to cartilage repair surgery and at 3 and 12 months follow-up. At similar time points clinical improvement After scout images, dGEMRIC scans were performed on a clinical 3-tesla MRI scanner (Achieva 3T; Philips Medical Systems) using a 16-channel knee coil. dGEMRIC (delayed Gadolinium Enhanced Magnetic Resonance Image of Cartilage) is a well-established technique for cartilage quality assessment in osteoarthritis at clinical field strengths.

LUM 6 – 2013 - Lunds universitet - doczz

Sport, 19,3, 442-452. Söderman, K., Pietila, T., magnetkameraundersökning (3D dGEMRIC). 145 000. Blåsfunktion bedöms med t.ex.

KNEE OSTEOARTHRITIS - Dissertations.se

The system gives 17 Nov 2015 cartilage (dGEMRIC) of the knee at 3.0 T in patients with early In addition to dGEMRIC scans, three routine sequences consisting of a fast MRI scans may not be able to be performed on patients who have a Cardiac and molecular techniques for quantitative cartilage analysis (dGEMRIC, T2 20x more radiation for CT scans of the hip and pelvis. In itself it is not significant but in repeated doses can be harmful.

Eleven hips (11 patients) underwent subsequent joint-preserving hip surgery. Ten hips (10 patients) underwent a surgical hip dislocationforFAI correction,andonehip (one The delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC) technique has shown promising results in pilot clinical studies of early osteoarthritis. Currently, its broader acceptance is lim-ited by the long scan time and the need for postprocessing to calculate the T1 maps. A fast T1 mapping imaging technique scans. The recent development of fast Spoiled Gradient Echo (fSPGR) 3D T1 mapping pulse sequences for dGEMRIC (3,4) has resulted in echo times under 3.0 millisecond, allowing for calculation of T1 Planar dGEMRIC Maps May Aid Imaging Assessment of Cartilage Damage in Femoroacetabular Impingement Bulat, Evgeny; Bixby, Sarah D.; Siversson, Carl LU; Kalish, Leslie A.; Warfield, Simon K. and Kim, Young-Jo () In Clinical Orthopaedics and Related Research 474 (2). p.467-478.
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38 hips in 31 patients who had a dGEMRIC scan and radiographic evidence of FAI were identified. Clinical symptoms were assessed using WOMAC questionnaire.
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LUM 6 – 2013 - Lunds universitet - doczz

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dGEMRIC and T2 mapping. Three hips were excluded as a result of incomplete scans owing to a software upgrade for. Fig. 5 Jun 2020 Images were analyzed by two independent raters for dGEMRIC indices, Conclusion: As examined by DCE MRI and dGEMRIC, there is a significant Use precise geolocation data, Actively scan device characteristics for Clinical examination, serum COMP level, and dGEMRIC scans (1.5 T) were performed at baseline and after 7 months. The dGEMRIC index (ms), reflecting av C Siversson — dGEMRIC delayed gadolinium-enhanced MRI of cartilage. FID apparent optimal time window for the MRI scan (at 90-120 minutes for knees) might actually be Human studies evaluating dGEMRIC as a prognostic tool for knee osteoarthritis.